![]() Of the 14 patients enrolled, 11 received at least one dose of toceranib. Patients were evaluated after three cycles (up to six doses) and progression free survival was calculated as the number of days from the start of therapy to progression of disease, death from any cause, or discontinuation for any reason. ![]() Doses were determined using the 3 + 3 design. Patients received oral toceranib (Bristol-Myers Squibb, New York, NY), a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 1 (VEGFR1), VEGFR2, and VEGFR3, every other day for 14 days in a 28-day cycle. This clinical trial evaluated the maximum tolerated dose of toceranib phosphate in patients with advanced STS. Patients with advanced soft-tissue sarcoma (STS) have an overall survival of between 12 and 15 months with standard cytotoxic therapy. ![]() xbox 360, 2k, NES, Roms, Tapes, Games, Cartridges,A dose-escalating study of toceranib phosphate monotherapy in patients with advanced soft-tissue sarcomas: a phase I trial. The Toa Mata of Kai proved too strong for the Brotherhood of Evil Mutants. Captain Tsubasa 2 NES Trilogy Misugi Hack By Wakashimazu 2012 HitĬaptain Tsubasa 2 NES Trilogy Misugi Hack By Wakashimazu 2012 hit
0 Comments
Leave a Reply. |